The proprietary strain L. paracasei, LPC-S01™ was isolated from the human vagina and as a first step was studied for its probiotic activity in key areas such as safety, acid and bile tolerance, adhesion & GI transit. Based on the results in these key areas, the strain was then evaluated for its probiotic benefit in female health through a randomized, placebo-controlled, double-blind cross-over study (Koirala R et al. FEMS Microbiology Ecology 2020, 96).
Product Key Features
- Oral dose/dietary supplement
- Supplied in powder, stick and capsule form
- Delivers minimum 24B cfu/dose
- Product has been studied in a human clinical study
Benefits
- Favors the balance of the gut microbiota
- It can contribute to the vaginal microbial balance
Scientific Evidence
Balzaretti S et al. Front. Microbiol. 2015; 6:952
- Recovery study, that demonstrated the capability of the strain to survive gastrointestinal transit in healthy adults
Koirala R et al. FEMS Microbiology Ecology 2020, 96
- Randomized, placebo-controlled, double-blind cross-over clinical trial on 40 healthy adult women
- The probiotic product, favoring the balance of the intestinal microbiota, was also able to contribute to a positive vaginal microbiota modulation:
- Increase concentrations of key Lactobacilli species including L. crispatus
- Decreased presence of G. vaginalis (increase G. vaginalis often leads to Bacterial Vaginosis)
- Decreasing trend of presence of other pathogenic bacteria
- Strain recovered also in vagina